| Date | Location | Result | |
| 02/26/22 | Sioux Falls, SD | Augustana (SD) 73, Southwest Minnesota 55 | Box score |
| 02/23/22 | Minot, ND | Southwest Minnesota 89, Minot State 75 | Box score |
| 02/19/22 | Sioux Falls, SD | Augustana (SD) 74, Southwest Minnesota 62 | Box score |
| 02/17/22 | Marshall, MN | Southwest Minnesota 60, Wayne State (NE) 55 (OT) | Box score |
| 02/12/22 | Winona, MN | Southwest Minnesota 79, Winona State 71 | Box score |
| 02/11/22 | Fayette, IA | Upper Iowa 67, Southwest Minnesota 56 | Box score |
| 02/05/22 | Marshall, MN | Concordia-St. Paul 61, Southwest Minnesota 60 | Box score |
| 02/04/22 | Marshall, MN | Southwest Minnesota 81, Minnesota State 71 | Box score |
| 01/29/22 | St. Cloud, MN | Southwest Minnesota 93, St. Cloud State 86 (2OT) | Box score |
| 01/28/22 | Duluth, MN | Minnesota Duluth 91, Southwest Minnesota 62 | Box score |
| 01/22/22 | Marshall, MN | Southwest Minnesota 72, Bemidji State 64 | Box score |
| 01/21/22 | Marshall, MN | Minnesota Crookston 70, Southwest Minnesota 67 | Box score |
| 01/14/22 | Aberdeen, SD | Northern State 69, Southwest Minnesota 68 | Box score |
| 01/08/22 | Marshall, MN | Southwest Minnesota 77, Mary 73 | Box score |
| 01/02/22 | Marshall, MN | Sioux Falls 72, Southwest Minnesota 71 (OT) | Box score |
| 12/18/21 | Mankato, MN | Southwest Minnesota 71, Minnesota State 69 (OT) | Box score |
| 12/17/21 | Saint Paul, MN | Southwest Minnesota 83, Concordia-St. Paul 70 | Box score |
| 12/11/21 | Marshall, MN | Upper Iowa 82, Southwest Minnesota 80 | Box score |
| 12/10/21 | Marshall, MN | Southwest Minnesota 50, Winona State 49 | Box score |
| 12/04/21 | Marshall, MN | Augustana (SD) 103, Southwest Minnesota 74 | Box score |
| 12/02/21 | Wayne, NE | Wayne State (NE) 68, Southwest Minnesota 65 | Box score |
| 11/29/21 | Marshall, MN | Southwest Minnesota 83, Minnesota Morris 60 | Box score |
| 11/23/21 | Sioux Falls, SD | Southwest Minnesota 70, Sioux Falls 69 | Box score |
| 11/20/21 | Kenosha, WI | Southwest Minnesota 73, Davenport 63 | Box score |
| 11/19/21 | Kenosha, WI | Southwest Minnesota 69, Wisconsin-Parkside 60 | Box score |
| 11/13/21 | Saint Paul, MN | Southwest Minnesota 84, Newman 58 | Box score |
| 11/12/21 | Saint Paul, MN | Rogers State 63, Southwest Minnesota 54 | Box score |